CRISPR-Cas9 Genome Editing System
Poonam Sharma
Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India
Parshant Kumar Sharma
Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India
Priya Sharma
Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India
O.P. Verma
Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India
Ashim Debnath*
Dept. of Genetics & Plant Breeding, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya, Uttar Pradesh (224 229), India
DOI: NIL
Keywords: Cas9 gene, CRISPR, Genome editing, Molecular Mechanism
Abstract
CRISPR/Cas9 is a versatile genome-editing tool that has been used to investigate the function of genetic components, create genetically modified creatures, and conduct preclinical research on genetic illnesses. It is a new approach that may precisely and accurately change any section of any species without affecting other gene. In this article, we look at the molecular mechanism, applications, and problems of CRISPR/Cas9-mediated genome editing, as well as the future clinical pharmacological properties of CRISPR/Cas9.
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Reference
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