CRISPR-CAS9: A Revolutionary Tool
Siba Prasad Kar*
Dept. of Biotechnology, Centurion University of Technology & Management, Jatni, Bhubaneswar, Odisha (752 050), India
Ashutosh Das
Dept. of Biotechnology, Centurion University of Technology & Management, Jatni, Bhubaneswar, Odisha (752 050), India
Ashirbad Swain
Dept. of Biotechnology, Centurion University of Technology & Management, Jatni, Bhubaneswar, Odisha (752 050), India
DOI: NIL
Keywords: CRISPR-CAS, DNA, Genome editing, RNA
Abstract
As we all know that DNA is responsible for the physical traits of the living organisms, we can change their characteristics by editing their DNA. This can be possible by addition or removal of specific genetic materials from the DNA. The technology used for this process is called genome editing and CRISPR-CAS is the most popular genome editing tool now-a-days. By CRISPR-CAS we can target a specific sequence of a DNA and add or remove genetic materials from that specific part according to our need. CRISPR-CAS has a guide RNA which is homologous to the DNA in which we want to change the genetic sequence, and a protein body which has two scissors to cut the targeted DNA strand. By the help of CRISPR-CAS crop improvement can be possible. It is also helpful for the treatment of many diseases.
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Reference
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