Genome Editing System for Insect Pest Management
Rajadurai Gothandaraman
Dept. of Plant Biotechnology, Centre for Plant Molecular Biology & Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu (641 003), India
DOI: NIL
Keywords: CRISPR/Cas, Genome editing, Pest management, pgSIT
Abstract
The recent advancement of gene-editing technologies such as Clustered Regularly Interspaced Short Palindromic Repeats and associated protein (CRISPR/Cas) has opened new doors for the development of novel pest control strategies. CRISPR/Cas provides stable genetic modifications within pest populations, allowing for basic exploratory research as well as support for efforts to suppress pest populations using gene drives. Highly efficient precision guided SIT (pgSIT) technology that can be deployed as eggs which exclusively give rise to sterile males. pgSIT is extremely robust at genetically sexing and simultaneously sterilizing the resulting progeny reproducibly with 100% efficiency.
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Reference
Bouyer, J., Vreysen, M.J.B., 2019. Concerns about the feasibility of using “precision guided sterile males” to control insects. Nat.Commun. 10, 3954. DOI: 10.1038/s41467-019-11616-9.
Dhaliwal, G.S., Jindal, V., Mohindru, B., 2015. Crop Losses due to insect pests: Global and Indian Scenario. Indian Journal of Entomology 77(2), 165- 168.
Fernández, C.R., 2021. CRISPR-Cas9: The Gene Editing Tool Changing the World. Available at: https://www.labiotech.eu/in-depth/crispr-cas9-review-gene-editing-tool/. Accessed on: 29 July 2022.
Kandul, N.P., Liu, J., Wu, S.L., Marshall, J.M., Akbari, O.S., 2019. Transforming insect population control with precision guided sterile males with demonstration in flies. Nat. Commun. 10, 84.
Wang, H., Russa, M.L., Lei, S.Q., 2016. CRISPR/Cas9 in Genome Editing and Beyond. Annual Review of Biochemistry 85, 227-64.