Gut Health and Diabetes: How Phytochemicals Can Help
Bharat Garg*
Dept. of Molecular Biology, Biotechnology and Bioinformatics, College of Biotechnology, CCS HAU, Hisar, Haryana (125 004), India
Shikha Yashveer
Dept. of Molecular Biology, Biotechnology and Bioinformatics, College of Biotechnology, CCS HAU, Hisar, Haryana (125 004), India
Anita
Dept. of Molecular Biology, Biotechnology and Bioinformatics, College of Biotechnology, CCS HAU, Hisar, Haryana (125 004), India
Shilpi
Dept. of Molecular Biology, Biotechnology and Bioinformatics, College of Biotechnology, CCS HAU, Hisar, Haryana (125 004), India
Reena Rani
Dept. of Molecular Biology, Biotechnology and Bioinformatics, College of Biotechnology, CCS HAU, Hisar, Haryana (125 004), India
DOI: NIL
Keywords: Diabetes, microbiota, phytochemicals, prebiotics
Abstract
The role of gut microbiota in developing and managing diabetes has received significant attention in recent years. Phytochemicals, biologically active compounds found in plants, have been proposed as potential modulators of gut microbiota in diabetes. Studies suggest that phytochemicals may positively impact gut microbiota composition and function in diabetes and improve glucose metabolism and insulin sensitivity. Further investigation is required to comprehensively comprehend the mechanisms responsible for these impacts and establish the most effective quantities and origins of phytochemicals. Mechanisms of action for phytochemicals include acting as prebiotics, reducing inflammation and oxidative stress, and affecting the production of short-chain fatty acids. Limitations and challenges associated with clinical studies include heterogeneity of study populations, lack of standardized methods for assessing gut microbiota, and small sample sizes. Future research can focus on human clinical trials, mechanistic studies, identifying novel phytochemicals, and personalized medicine approaches.
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Reference
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