
Implications of Stem Cell Therapy in Cancer Treatment
Saswati Das*
Dept. of Biotechnology, Centurion University of Technology and Management, Jatni, Bhubaneswar, Odisha (752050), India
Debanjana Saha
Dept. of Biotechnology, Centurion University of Technology and Management, Jatni, Bhubaneswar, Odisha (752050), India
DOI: NIL
Keywords: Cancer, Metastasis, Stem cells, Transplant
Abstract
Cancer is a complex heterogeneous illness that posses particular barriers to its management. The survival of cancer patients increased dramatically, mostly due to multidisciplinary treatment and advanced chemotherapy. Despite recent advancements, many patients with solid tumors continue to undergo recurrence following adjuvant therapy, and their survival remains poor when their cancer is no longer limited to their lungs, as well as when advanced cancer is rarely cured. Over the years, the series of stem cell biology results has produced new possible methods through its unusual biological behaviour, including self-renewal, lateral migration, differentiation and modulatory effects on other cells, to cure cancer patients. In this article, we discuss the specific biological behaviour possessed by different types of stem cells along with the mechanisms associated with various stem cells for cancer care. We also emphasize on the obstacles encountered, along with the risk factors associated with them.
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Reference
Chu, C.T., Nguyen, T.T., Tien, N.L.B., Tran, D.K., Jeong, J.H., Anh, P.G., Thanh, V.V., Truong, D.T., Dinh, T.C., 2020. Recent progress of stem cell therapy in cancer treatment: Molecular Mechanisms and Potential Applications. Cells 9(3), 563.
Lin, W., Huang, L., Li, Y., Fang, B., Li, G., Chen, L., Xu, L., 2019. Mesenchymal stem cells and cancer: Clinical challenges and opportunities. Biomed Res Int.
Dawood, S., Austin, L., Cristofanilli, M., 2014. Cancer stem cells: implications for cancer therapy. Oncology (Williston Park) 28(12), 1101-7, 1110.