Importance of Sialic Acid Receptor and RIG-I in Innate Immune Response of Poultry
A. Varun
Post Graduate Research Institute in Animal Sciences (PGRIAS), TANUVAS, Kattupakkam, Kanchipuram, Tamil Nadu (603 203), India
T. Chandrasekar*
Veterinary College and Research Institute (VC&RI), TANUVAS, Theni, Tamil Nadu (625 602), India
K. Senthilkumar
Post Graduate Research Institute in Animal Sciences (PGRIAS), TANUVAS, Kattupakkam, Kanchipuram, Tamil Nadu (603 203), India
Karu Pasupathy
Post Graduate Research Institute in Animal Sciences (PGRIAS), TANUVAS, Kattupakkam, Kanchipuram, Tamil Nadu (603 203), India
DOI: NIL
Keywords: Innate immune response, Poultry, RIG-I, Sialic Acid
Abstract
Avian influenza is a viral infection found in domestic poultry and a wide range of other birds. Wild waterfowl and shorebirds are often asymptomatic carriers. RIG-I (retinoic acid-inducible gene I) and Toll like Receptors (TLRs) are well expressed in water fowls. In contract to this RIG-I gene were absent in chicken genome and makes the poultry more susceptible. Avian influenza outbreaks occur in poultry, depopulation (stamping out) of infected flocks is carried out with biosecurity measures.
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Reference
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