Stress Relieving Tetrodotoxin from Pufferfishes
R. Karthik*
ICAR- Central Institute of Fisheries Education, Versova, Mumbai, Maharashtra (400 061), India
S. Sudarshan
ICAR- Central Institute of Fisheries Education, Versova, Mumbai, Maharashtra (400 061), India
S. Aanand
Erode Centre for Sustainable Aquaculture, Bhavanisagar, Erode, Tamil Nadu (638 451), India
DOI: NIL
Keywords: CRH-ACTH-cortisol axis, Pufferfishes, Stress, Tetrodotoxin
Abstract
Pufferfishes occupies its unique place in Japanese seafood restaurants because of its delicious nature. Takifugu rubripes, an IUCN near-threatened red-listed species is one of the most preferred species and widely consumed. Due to its high market demand, makes it a highly prized food fish which in turn leads to depletion of wild stocks by overfishing. Aquacultured Tiger pufferfishes meets out the demand to a small extent but still consumer’s preference relies on those wild caught ones. Presently, Tiger pufferfish hatcheries faces severe stress releated mortalities. This article deals with the aspects that how the Tetrodotoxin, a potent neurotoxin mitigates those stress-related mortalities in Tiger Pufferfishes hatcheries. And also, explains that how understanding on the interactive effects of tetrodotoxin on CRH-ACTH-cortisol axis and its mitigating stress effect can be exploited through further research.
Downloads
not found
Reference
Amano, M., Amiya, N., Takaoka, M., Sato, H., Takatani, T., Arakawa, O., Sakakura, Y., 2019. Tetrodotoxin functions as a stress relieving substance in juvenile tiger puffer Takifugu rubripes. Toxicon 171, 54-61.
Islam, Q.T., Razzak, M.A., Islam, M.A., Bari, M.I., Basher, A., Chowdhury, F.R., Sayeduzzaman, A.B.M., Ahasan, H.A.M.N., Faiz, M.A., Arakawa, O., Yotsu-Yamashita, M., 2011. Puffer fish poisoning in Bangladesh: clinical and toxicological results from large outbreaks in 2008. Transactions of the Royal Society of Tropical Medicine and Hygiene 105(2), 74-80.
Ma, A.J., Lu, L.J., Chen, C., Wang, X.A., Meng, X.S., Li, W.Y., Liu, S.C., 2011. Breeding and genetic research of major economic species of Fugu. Marine Science 35(11), 128-133.
Noguchi, T., Arakawa, O., Takatani, T., 2006. TTX accumulation in pufferfish. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 1(1), 145-152.
Shao, K., Liu, M., Jing, L., Hardy, G., Leis, J.L., Matsuura, K., 2014. Takifugu rubripes (Temminck & Schlegel, 1850). The IUCN Red List of Threatened Species 2014: https://doi.org/10.2305/IUCN.UK.2014-3.RLTS.T193612A2247747.en